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The trial involved 1879 patients with inadequate glycemic control on metformin monotherapy, who were randomly assigned to receive tirzepatide at doses of 5 mg, 10 mg, or 15 mg, or semaglutide at a dose of 1 mg.After 40 weeks of treatment, all doses of tirzepatide were found to be noninferior and superior to semaglutide in terms of reducing glycated hemoglobin (HbA1c) levels

Disruption by androgens, inflammation, oxidative stress, or microvascular compromise shortens anagen and miniaturizes follicles

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These symptoms typically emerge when doses increase and diminish as the body adjusts

Komada, M., Takao, K

Lancet 376 , 419430 (2010)